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Tolnim Tablet is a combination of two medicines: Nimesulide and Tolperisone which relieve muscle pain

Generic Name:

Tolperisone + Nimesulide

Dosage form:


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Tolnim Tablet is a combination of two medicines: Nimesulide and Tolperisone which relieve muscle pain. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Tolperisone is a muscle relaxant. It works by acting on the centers in the brain and spinal cord to relieve the muscle stiffness or spasm.


Each Tablet contains:

  • Tolperisone 150 mg + Nimesulide 100 mg


Tolnim Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

It is unsafe to consume alcohol with Tolnim Tablet.

Tolnim Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.


Efficacy and tolerance of repeated oral doses of tolperisone hydrochloride in the treatment of painful reflex muscle spasm: results of a prospective placebo-controlled double-blind trial

The overall assessment of efficacy by the patient also demonstrated significant differences in favor of tolperisone hydrochloride. Best results were seen in patients aged between 40 and 60 years with a history of complaints shorter than 1 year and with concomitant physical therapy. The evaluation of safety data, i.e. adverse events, biochemical and hematological laboratory parameters, demonstrated no differences between tolperisone hydrochloride and placebo. As a conclusion tolperisone hydrochloride represents an effective and safe treatment of painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants

Pain. 67(2):417–425, OCT 1996 DOI: 10.1016/0304-3959(96)03187-9, PMID: 8951937


Tolnim is also available online in Medplus Mart, 1mg, Pharmeasy, Myupchar, Sasta Sunder.com, Med plus, Med near and save on medicals.

You may buy Tolnim by clicking any of online store.



It belongs to a group of drugs known as non-steroidal anti-inflammatory drugs (NSAID). This medicine performs its action by obstructing the release of specific chemical in the brain that are responsible for pain, fever, and swelling (redness).

What are the instructions for storage and disposal TOLNIM TABLET?

What are the contraindications to TOLNIM TABLET?

Will TOLNIM TABLET be more effective if taken in more than the recommended dose?

Can I take TOLNIM TABLET with paracetamol?

Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment. For more information we strongly recommend you see a doctor immediately.